HIV Target gene Detail Information

> CORIN Gene Search Result

Gene Information

Gene Name	CORIN
Gene ID	10699
Gene Full Name	corin, serine peptidase
Gene Alias	CRN; ATC2; Lrp4; PEE5; TMPRSS10
Transcripts	ENSG00000145244
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Actin filaments;Nuclear bodies;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9Y5Q5
HGNC ID	HGNC:19012
VEGA ID	OTTHUMG00000099441
OMIM ID	605236
String ID	9606.ENSP00000273857
PharmGKB ID	PA134972424

Target gene [CORIN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4015394	chr4	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CORIN expression and immune infiltrating cell level correlation result in HIV+ samples
CORIN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).