HTLV1 Target gene Detail Information

> COQ5 Gene Search Result

Gene Information

Gene Name	COQ5
Gene ID	84274
Gene Full Name	coenzyme Q5, methyltransferase
Transcripts	ENSG00000110871
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoli;Mitochondria;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q5HYK3
HGNC ID	HGNC:28722
VEGA ID	OTTHUMG00000169375
OMIM ID	616359
String ID	9606.ENSP00000288532
PharmGKB ID	PA143485438

Target gene [COQ5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000024	chr12	4323	2775	1247	8345	View
6000025	chr12	4323	2775	1247	8345	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of COQ5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COQ5 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of COQ5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COQ5 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of COQ5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COQ5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).