HIV Target gene Detail Information

> COPZ1 Gene Search Result

Gene Information

Gene Name	COPZ1
Gene ID	22818
Gene Full Name	coatomer protein complex subunit zeta 1
Gene Alias	COPZ; CGI-120; HSPC181; zeta-COP; zeta1-COP
Transcripts	ENSG00000111481
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	P61923
HGNC ID	HGNC:2243
VEGA ID	OTTHUMG00000169762
OMIM ID	615472
String ID	9606.ENSP00000449270
PharmGKB ID	PA26760

Target gene [COPZ1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002673	chr12	78	5	1	84	View
4004198	chr12	32	7	9	48	View
4006554	chr12	24			24	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of COPZ1 expression and immune infiltrating cell level correlation result in HIV+ samples
COPZ1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of COPZ1 expression and immune infiltrating cell level correlation result in HIV+ samples
COPZ1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).