HIV Target gene Detail Information

> COPB1 Gene Search Result


Gene Information
Gene Name COPB1
Gene ID 1315
Gene Full Name coatomer protein complex subunit beta 1
Gene Alias COPB
Transcripts ENSG00000129083
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Golgi apparatus;Vesicles;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P53618
HGNC ID HGNC:2231
VEGA ID OTTHUMG00000165824
OMIM ID 600959
String ID 9606.ENSP00000249923
PharmGKB ID PA26747
Target gene [COPB1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4008392 chr11 14 1 15 View
4013378 chr11 2 1 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of COPB1 expression and immune infiltrating cell level correlation result in HIV+ samples
COPB1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of COPB1 expression and immune infiltrating cell level correlation result in HIV+ samples
COPB1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).