HBV Target gene Detail Information

> COL6A3 Gene Search Result


Gene Information
Gene Name COL6A3
Gene ID 1293
Gene Full Name collagen type VI alpha 3 chain
Gene Alias DYT27; UCMD1; BTHLM1
Transcripts ENSG00000163359
Virus HBV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;Vesicles;Predicted to be secreted;
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P12111
HGNC ID HGNC:2213
VEGA ID OTTHUMG00000150020
OMIM ID 120250
String ID 9606.ENSP00000295550
PharmGKB ID PA26729
Target gene [COL6A3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009099 chr2 13 4 17 View
1402910 chr2 13 4 17 View
1404859 chr2 97 81 13 191 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of COL6A3 expression and immune infiltrating cell level correlation result in HBV+ samples
COL6A3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).