HBV Target gene Detail Information

> COL5A1 Gene Search Result

Gene Information

Gene Name	COL5A1
Gene ID	1289
Gene Full Name	collagen type V alpha 1 chain
Gene Alias	EDSC; EDSCL1
Transcripts	ENSG00000130635
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;Predicted to be secreted;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	P20908
HGNC ID	HGNC:2209
VEGA ID	OTTHUMG00000020891
OMIM ID	120215
String ID	9606.ENSP00000360882
PharmGKB ID	PA26724

Target gene [COL5A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1017972	chr9				0	View
1401029	chr9				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of COL5A1 expression and immune infiltrating cell level correlation result in HBV+ samples
COL5A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).