HBV Target gene Detail Information

> COL4A6 Gene Search Result

Gene Information

Gene Name	COL4A6
Gene ID	1288
Gene Full Name	collagen type IV alpha 6 chain
Gene Alias	DFNX6; DELXq22.3; CXDELq22.3
Transcripts	ENSG00000197565
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Predicted to be secreted;
HPA Protein Class Info	Disease related genes, Predicted secreted proteins
Uniport_ID	Q14031
HGNC ID	HGNC:2208
VEGA ID	OTTHUMG00000022179
OMIM ID	303631
String ID	9606.ENSP00000378340
PharmGKB ID	PA26723

Target gene [COL4A6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1015948	chrX	2			2	View
1016715	chrX		1		1	View
1016716	chrX		1		1	View
1404587	chrX	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of COL4A6 expression and immune infiltrating cell level correlation result in HBV+ samples
COL4A6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).