HBV Target gene Detail Information

> COL18A1 Gene Search Result

Gene Information

Gene Name	COL18A1
Gene ID	80781
Gene Full Name	collagen type XVIII alpha 1 chain
Gene Alias	KS; KNO; KNO1
Transcripts	ENSG00000182871
Virus	HBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Predicted to be secreted;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	P39060
HGNC ID	HGNC:2195
VEGA ID	OTTHUMG00000090407
OMIM ID	120328
String ID	9606.ENSP00000347665
PharmGKB ID	PA26711

Target gene [COL18A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006396	chr21	3	36		39	View
1007644	chr21	25			25	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of COL18A1 expression and immune infiltrating cell level correlation result in HBV+ samples
COL18A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).