HTLV1 Target gene Detail Information

> COG7 Gene Search Result

Gene Information

Gene Name	COG7
Gene ID	91949
Gene Full Name	component of oligomeric golgi complex 7
Gene Alias	CDG2E
Transcripts	ENSG00000168434
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	P83436
HGNC ID	HGNC:18622
VEGA ID	OTTHUMG00000094807
OMIM ID	606978
String ID	9606.ENSP00000305442
PharmGKB ID	PA38605

Target gene [COG7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6005886	chr16	27	34	18	79	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of COG7 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COG7 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of COG7 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COG7 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of COG7 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COG7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).