HIV Target gene Detail Information

> COA1 Gene Search Result

Gene Information

Gene Name	COA1
Gene ID	55744
Gene Full Name	cytochrome c oxidase assembly factor 1 homolog
Gene Alias	C7orf44; MITRAC15
Transcripts	ENSG00000106603
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9GZY4
HGNC ID	HGNC:21868
VEGA ID	OTTHUMG00000128949
OMIM ID	614769
String ID	9606.ENSP00000379218
PharmGKB ID	PA162380473

Target gene [COA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001449	chr2	152	2	9	163	View
4004724	chr2	9	31		40	View
4006768	chr2	20	3		23	View
4009483	chr7	7	4		11	View
4012101	chr2	2	2	1	5	View
4014735	chr2	2			2	View
4014947	chr7		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of COA1 expression and immune infiltrating cell level correlation result in HIV+ samples
COA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).