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HIV Target gene Detail Information

> CNOT6L Gene Search Result


Gene Information
Gene Name CNOT6L
Gene ID 246175
Gene Full Name CCR4-NOT transcription complex subunit 6 like
Gene Alias CCR4b
Transcripts ENSG00000138767
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q96LI5
HGNC ID HGNC:18042
VEGA ID OTTHUMG00000160832
OMIM ID 618069
String ID 9606.ENSP00000424896
PharmGKB ID PA38480
Target gene [CNOT6L] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4005864 chr4 11 16 2 29 View
4009476 chr4 6 1 4 11 View
4009757 chr4 11 11 View
4010221 chr4 9 9 View
4013486 chr4 1 2 3 View
4013701 chr4 1 2 3 View
4014072 chr4 2 2 View
4014225 chr4 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CNOT6L expression and immune infiltrating cell level correlation result in HIV+ samples
CNOT6L expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CNOT6L expression and immune infiltrating cell level correlation result in HIV+ samples
CNOT6L expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).