HBV Target gene Detail Information

> CNOT4 Gene Search Result

Gene Information

Gene Name	CNOT4
Gene ID	4850
Gene Full Name	CCR4-NOT transcription complex subunit 4
Gene Alias	NOT4; NOT4H; CLONE243
Transcripts	ENSG00000080802
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Transcription factors
Uniport_ID	O95628
HGNC ID	HGNC:7880
VEGA ID	OTTHUMG00000155568
OMIM ID	604911
String ID	9606.ENSP00000445508
PharmGKB ID	PA26675

Target gene [CNOT4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011462	chr7	3	6		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CNOT4 expression and immune infiltrating cell level correlation result in HBV+ samples
CNOT4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).