HIV Target gene Detail Information

> CNGB1 Gene Search Result

Gene Information

Gene Name	CNGB1
Gene ID	1258
Gene Full Name	cyclic nucleotide gated channel beta 1
Gene Alias	CNG4; GAR1; GARP; RP45; CNCG2; CNCG4; GARP2; RCNC2; RCNCb; CNCG3L; CNGB1B; RCNCbeta
Transcripts	ENSG00000070729
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q14028
HGNC ID	HGNC:2151
VEGA ID	OTTHUMG00000154810
OMIM ID	600724
String ID	9606.ENSP00000251102
PharmGKB ID	PA26662

Target gene [CNGB1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001214	chr16	84	21	87	192	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CNGB1 expression and immune infiltrating cell level correlation result in HIV+ samples
CNGB1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CNGB1 expression and immune infiltrating cell level correlation result in HIV+ samples
CNGB1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).