HIV Target gene Detail Information

> CMTM6 Gene Search Result

Gene Information

Gene Name	CMTM6
Gene ID	54918
Gene Full Name	CKLF like MARVEL transmembrane domain containing 6
Gene Alias	CKLFSF6; PRO2219
Transcripts	ENSG00000091317
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9NX76
HGNC ID	HGNC:19177
VEGA ID	OTTHUMG00000130747
OMIM ID	607889
String ID	9606.ENSP00000205636
PharmGKB ID	PA38816

Target gene [CMTM6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000890	chr3	58	127	69	254	View
4005832	chr3	23	6		29	View
4008887	chr3	11	1	1	13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CMTM6 expression and immune infiltrating cell level correlation result in HIV+ samples
CMTM6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CMTM6 expression and immune infiltrating cell level correlation result in HIV+ samples
CMTM6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).