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HBV Target gene Detail Information

> CLYBL Gene Search Result


Gene Information
Gene Name CLYBL
Gene ID 171425
Gene Full Name citrate lyase beta like
Gene Alias CLB
Transcripts ENSG00000125246
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8N0X4
HGNC ID HGNC:18355
VEGA ID OTTHUMG00000017278
OMIM ID 609686
String ID 9606.ENSP00000365533
PharmGKB ID PA26622
Target gene [CLYBL] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004283 chr13 43 25 18 86 View
1402911 chr13 43 25 18 86 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of CLYBL expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
CLYBL expression: Low -> High
Lollipop of CLYBL expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of CLYBL expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CLYBL expression and immune infiltrating cell level correlation result in HBV+ samples
CLYBL expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).