HBV Target gene Detail Information

> CLTC Gene Search Result

Gene Information

Gene Name	CLTC
Gene ID	1213
Gene Full Name	clathrin heavy chain
Gene Alias	Hc; CHC; CHC17; MRD56; CLH-17; CLTCL2
Transcripts	ENSG00000141367
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endosomes;Lysosomes;Vesicles;Cytosol;Mitotic spindle;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q00610
HGNC ID	HGNC:2092
VEGA ID	OTTHUMG00000134279
OMIM ID	118955
String ID	9606.ENSP00000479606
PharmGKB ID	PA26618

Target gene [CLTC] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005300	chr17	41	16		57	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CLTC expression and immune infiltrating cell level correlation result in HBV+ samples
CLTC expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).