HIV Target gene Detail Information

> CLTA Gene Search Result

Gene Information

Gene Name	CLTA
Gene ID	1211
Gene Full Name	clathrin light chain A
Gene Alias	LCA
Transcripts	ENSG00000122705
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endosomes;Lysosomes;Vesicles;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	P09496
HGNC ID	HGNC:2090
VEGA ID	OTTHUMG00000019896
OMIM ID	118960
String ID	9606.ENSP00000242285
PharmGKB ID	PA26616

Target gene [CLTA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008838	chr9	14			14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CLTA expression and immune infiltrating cell level correlation result in HIV+ samples
CLTA expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CLTA expression and immune infiltrating cell level correlation result in HIV+ samples
CLTA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).