HIV Target gene Detail Information

> CLSTN1 Gene Search Result

Gene Information

Gene Name	CLSTN1
Gene ID	22883
Gene Full Name	calsyntenin 1
Gene Alias	CST-1; CSTN1; CDHR12; PIK3CD; ALC-ALPHA; XB31alpha; alcalpha1; alcalpha2
Transcripts	ENSG00000171603
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted membrane proteins
Uniport_ID	O94985
HGNC ID	HGNC:17447
VEGA ID	OTTHUMG00000001451
OMIM ID	611321
String ID	9606.ENSP00000366513
PharmGKB ID	PA38238

Target gene [CLSTN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003585	chr1	6	52		58	View
4011150	chr1	7			7	View
4011645	chr1	5	1		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CLSTN1 expression and immune infiltrating cell level correlation result in HIV+ samples
CLSTN1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CLSTN1 expression and immune infiltrating cell level correlation result in HIV+ samples
CLSTN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).