HIV Target gene Detail Information

> CLPX Gene Search Result

Gene Information

Gene Name	CLPX
Gene ID	10845
Gene Full Name	caseinolytic mitochondrial matrix peptidase chaperone subunit
Gene Alias	EPP2
Transcripts	ENSG00000166855
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;Cytosol;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O76031
HGNC ID	HGNC:2088
VEGA ID	OTTHUMG00000133139
OMIM ID	615611
String ID	9606.ENSP00000300107
Drugbank ID	BE0003089
PharmGKB ID	PA26614

Target gene [CLPX] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009138	chr15	8	4		12	View
4010559	chr15	7	1		8	View
4011365	chr15	7			7	View
4011980	chr15		6		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CLPX expression and immune infiltrating cell level correlation result in HIV+ samples
CLPX expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CLPX expression and immune infiltrating cell level correlation result in HIV+ samples
CLPX expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).