Home
Virus
Gene
Disease
Dataset
Download
Help
 
HPV Target gene Detail Information

> CLNK Gene Search Result


Gene Information
Gene Name CLNK
Gene ID 116449
Gene Full Name cytokine dependent hematopoietic cell linker
Gene Alias MIST
Transcripts ENSG00000109684
Virus HPV
Gene Type protein coding
HPA Location Info Vesicles;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q7Z7G1
HGNC ID HGNC:17438
VEGA ID OTTHUMG00000160062
OMIM ID 611434
String ID 9606.ENSP00000226951
PharmGKB ID PA164718067
Target gene [CLNK] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5004051 chr4 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of CLNK expression and immune infiltrating cell level correlation result in HPV+ samples
CLNK expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of CLNK expression and immune infiltrating cell level correlation result in HPV+ samples
CLNK expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of CLNK expression and immune infiltrating cell level correlation result in HPV+ samples
CLNK expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of CLNK expression and immune infiltrating cell level correlation result in HPV+ samples
CLNK expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of CLNK expression and immune infiltrating cell level correlation result in HPV+ samples
CLNK expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of CLNK expression and immune infiltrating cell level correlation result in HPV+ samples
CLNK expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).