HIV Target gene Detail Information

> CLIC2 Gene Search Result


Gene Information
Gene Name CLIC2
Gene ID 1193
Gene Full Name chloride intracellular channel 2
Gene Alias CLIC2b; MRXS32; XAP121
Transcripts ENSG00000155962
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;Nucleoplasm;
HPA Protein Class Info Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID O15247
HGNC ID HGNC:2063
VEGA ID OTTHUMG00000022660
OMIM ID 300138
String ID 9606.ENSP00000358460
PharmGKB ID PA26589
Target gene [CLIC2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4012012 chrX 6 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CLIC2 expression and immune infiltrating cell level correlation result in HIV+ samples
CLIC2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).