HIV Target gene Detail Information

> CLEC4A Gene Search Result

Gene Information

Gene Name	CLEC4A
Gene ID	50856
Gene Full Name	C-type lectin domain family 4 member A
Gene Alias	DCIR; LLIR; CD367; DDB27; CLECSF6; HDCGC13P
Transcripts	ENSG00000111729
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9UMR7
HGNC ID	HGNC:13257
OMIM ID	605306
String ID	9606.ENSP00000229332
PharmGKB ID	PA26584

Target gene [CLEC4A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007382	chr12	11	8		19	View
4007824	chr12	9	8		17	View
4011184	chr12	4	3		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CLEC4A expression and immune infiltrating cell level correlation result in HIV+ samples
CLEC4A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CLEC4A expression and immune infiltrating cell level correlation result in HIV+ samples
CLEC4A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).