HIV Target gene Detail Information

> CLEC2D Gene Search Result

Gene Information

Gene Name	CLEC2D
Gene ID	29121
Gene Full Name	C-type lectin domain family 2 member D
Gene Alias	CLAX; LLT1; OCIL
Transcripts	ENSG00000069493
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9UHP7
HGNC ID	HGNC:14351
VEGA ID	OTTHUMG00000168369
OMIM ID	605659
String ID	9606.ENSP00000261340
PharmGKB ID	PA142672100

Target gene [CLEC2D] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004595	chr12	32	8	2	42	View
4006778	chr12	5	12	6	23	View
4007964	chr12	14	3		17	View
4011873	chr12	3	3		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CLEC2D expression and immune infiltrating cell level correlation result in HIV+ samples
CLEC2D expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CLEC2D expression and immune infiltrating cell level correlation result in HIV+ samples
CLEC2D expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).