HPV Target gene Detail Information

> CLEC19A Gene Search Result


Gene Information
Gene Name CLEC19A
Gene ID 728276
Gene Full Name C-type lectin domain containing 19A
Transcripts ENSG00000261210
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted secreted proteins
Uniport_ID Q6UXS0
HGNC ID HGNC:34522
VEGA ID OTTHUMG00000177218
String ID 9606.ENSP00000455948
PharmGKB ID PA165449848
Target gene [CLEC19A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403205 chr16 2 2 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of CLEC19A expression and immune infiltrating cell level correlation result in HPV+ samples
CLEC19A expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of CLEC19A expression and immune infiltrating cell level correlation result in HPV+ samples
CLEC19A expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of CLEC19A expression and immune infiltrating cell level correlation result in HPV+ samples
CLEC19A expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of CLEC19A expression and immune infiltrating cell level correlation result in HPV+ samples
CLEC19A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).