HIV Target gene Detail Information

> CLEC16A Gene Search Result

Gene Information

Gene Name	CLEC16A
Gene ID	23274
Gene Full Name	C-type lectin domain containing 16A
Gene Alias	Gop-1; KIAA0350
Transcripts	ENSG00000038532
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q2KHT3
HGNC ID	HGNC:29013
VEGA ID	OTTHUMG00000152915
OMIM ID	611303
String ID	9606.ENSP00000387122
PharmGKB ID	PA162382340

Target gene [CLEC16A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001330	chr16	41	63	73	177	View
4005695	chr16	14	16		30	View
4012902	chr16	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CLEC16A expression and immune infiltrating cell level correlation result in HIV+ samples
CLEC16A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CLEC16A expression and immune infiltrating cell level correlation result in HIV+ samples
CLEC16A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).