HBV Target gene Detail Information

> CLEC14A Gene Search Result


Gene Information
Gene Name CLEC14A
Gene ID 161198
Gene Full Name C-type lectin domain containing 14A
Gene Alias CEG1; EGFR-5; C14orf27
Transcripts ENSG00000176435
Virus HBV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;Golgi apparatus;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID Q86T13
HGNC ID HGNC:19832
VEGA ID OTTHUMG00000140248
OMIM ID 616845
String ID 9606.ENSP00000353013
Drugbank ID BE0005395
PharmGKB ID PA134890576
Target gene [CLEC14A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002167 chr14 301 18 4 323 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CLEC14A expression and immune infiltrating cell level correlation result in HBV+ samples
CLEC14A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).