HPV Target gene Detail Information

> CLDN16 Gene Search Result

Gene Information

Gene Name	CLDN16
Gene ID	10686
Gene Full Name	claudin 16
Gene Alias	HOMG3; PCLN1
Transcripts	ENSG00000113946
Virus	HPV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q9Y5I7
HGNC ID	HGNC:2037
VEGA ID	OTTHUMG00000156215
OMIM ID	603959
String ID	9606.ENSP00000264734
Drugbank ID	BE0010119
PharmGKB ID	PA26563

Target gene [CLDN16] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5300245	chr3	7	4		11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of CLDN16 expression and immune infiltrating cell level correlation result in HPV+ samples
CLDN16 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).