HTLV1 Target gene Detail Information

> CLDN12 Gene Search Result

Gene Information

Gene Name	CLDN12
Gene ID	9069
Transcripts	ENSG00000157224
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	P56749
HGNC ID	HGNC:2034
VEGA ID	OTTHUMG00000156612
OMIM ID	611232
String ID	9606.ENSP00000287916
PharmGKB ID	PA26560

Target gene [CLDN12] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6002164	chr7	171	96	9	276	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of CLDN12 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CLDN12 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of CLDN12 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CLDN12 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of CLDN12 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CLDN12 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).