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HBV Target gene Detail Information

> CLDN10 Gene Search Result


Gene Information
Gene Name CLDN10
Gene ID 9071
Gene Full Name claudin 10
Gene Alias OSPL; HELIX; OSP-L; CPETRL3
Transcripts ENSG00000134873
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P78369
HGNC ID HGNC:2033
VEGA ID OTTHUMG00000017217
OMIM ID 617579
String ID 9606.ENSP00000299339
PharmGKB ID PA26558
Target gene [CLDN10] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000991 chr13 513 370 335 1218 View
1001515 chr13 321 258 74 653 View
1001886 chr13 123 248 65 436 View
1001954 chr13 91 247 65 403 View
1001958 chr13 88 247 65 400 View
1002953 chr13 51 162 15 228 View
1002954 chr13 51 162 15 228 View
1004252 chr13 4 84 88 View
1004268 chr13 3 84 87 View
1004269 chr13 3 84 87 View
1004278 chr13 3 84 87 View
1014325 chr13 3 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of CLDN10 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
CLDN10 expression: Low -> High
Lollipop of CLDN10 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of CLDN10 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CLDN10 expression and immune infiltrating cell level correlation result in HBV+ samples
CLDN10 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).