HIV Target gene Detail Information

> CLDN1 Gene Search Result

Gene Information

Gene Name	CLDN1
Gene ID	9076
Gene Full Name	claudin 1
Gene Alias	CLD1; SEMP1; ILVASC
Transcripts	ENSG00000163347
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Gene Function	Suppressor gene
Uniport_ID	O95832
HGNC ID	HGNC:2032
VEGA ID	OTTHUMG00000156214
OMIM ID	603718
String ID	9606.ENSP00000295522
PharmGKB ID	PA26557

Target gene [CLDN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007463	chr3	12	7		19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CLDN1 expression and immune infiltrating cell level correlation result in HIV+ samples
CLDN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).