HPV Target gene Detail Information

> CHST2 Gene Search Result

Gene Information

Gene Name	CHST2
Gene ID	9435
Gene Full Name	carbohydrate sulfotransferase 2
Gene Alias	C6ST; GST2; GST-2; Gn6ST-1; HEL-S-75; glcNAc6ST-1
Transcripts	ENSG00000175040
Virus	HPV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Cytosol;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9Y4C5
HGNC ID	HGNC:1970
VEGA ID	OTTHUMG00000159351
OMIM ID	603798
String ID	9606.ENSP00000307911
PharmGKB ID	PA26502

Target gene [CHST2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5300029	chr7	111	1	1	113	View
5300030	chr7	10	2		12	View
5300031	chr7	1		12	13	View
5404810	chr3	4	8	2	14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE40774 (GEO)	Head and neck squamous cell carcinoma	134	Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE138080 (GEO)	Cervical intraepithelial neoplasia	25	Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE40774
HeatMap of cell type fractions in all samples	Lollipop of CHST2 expression and immune infiltrating cell level correlation result in HPV+ samples
CHST2 expression: Low -> High

> Dataset: GSE138080
HeatMap of cell type fractions in all samples	Lollipop of CHST2 expression and immune infiltrating cell level correlation result in HPV+ samples
CHST2 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of CHST2 expression and immune infiltrating cell level correlation result in HPV+ samples
CHST2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).