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HBV Target gene Detail Information

> CHST11 Gene Search Result


Gene Information
Gene Name CHST11
Gene ID 50515
Gene Full Name carbohydrate sulfotransferase 11
Gene Alias C4ST; C4ST1; OCBMD; C4ST-1; HSA269537
Transcripts ENSG00000171310
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q9NPF2
HGNC ID HGNC:17422
VEGA ID OTTHUMG00000169803
OMIM ID 610128
String ID 9606.ENSP00000305725
PharmGKB ID PA134875681
Target gene [CHST11] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003699 chr12 37 24 55 116 View
1005401 chr12 40 1 14 55 View
1010321 chr12 2 9 1 12 View
1019315 chr12 0 View
1403286 chr12 2 9 1 12 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of CHST11 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
CHST11 expression: Low -> High
Lollipop of CHST11 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of CHST11 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CHST11 expression and immune infiltrating cell level correlation result in HBV+ samples
CHST11 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).