HBV Target gene Detail Information

> CHRNB1 Gene Search Result

Gene Information

Gene Name	CHRNB1
Gene ID	1140
Gene Full Name	cholinergic receptor nicotinic beta 1 subunit
Gene Alias	ACHRB; CHRNB; CMS1D; CMS2A; CMS2C; SCCMS
Transcripts	ENSG00000283946
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	P11230
HGNC ID	HGNC:1961
VEGA ID	OTTHUMG00000108139
OMIM ID	100710
String ID	9606.ENSP00000304290
PharmGKB ID	PA26494

Target gene [CHRNB1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1400117	chr17	3066	379	308	3753	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CHRNB1 expression and immune infiltrating cell level correlation result in HBV+ samples
CHRNB1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).