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HPV Target gene Detail Information

> CHMP4B Gene Search Result


Gene Information
Gene Name CHMP4B
Gene ID 128866
Gene Full Name charged multivesicular body protein 4B
Gene Alias SNF7; CTPP3; Shax1; CHMP4A; SNF7-2; VPS32B; CTRCT31; Vps32-2; C20orf178; dJ553F4.4
Transcripts ENSG00000101421
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q9H444
HGNC ID HGNC:16171
VEGA ID OTTHUMG00000032272
OMIM ID 610897
String ID 9606.ENSP00000217402
PharmGKB ID PA25721
Target gene [CHMP4B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5200001 chr20 28 5 1 34 View
5200015 chr20 4 4 View
5200019 chr20 76 10 4 90 View
5200024 chr20 41 1 42 View
5200026 chr20 14 2 16 View
5200032 chr20 13 3 16 View
5200045 chr20 28 5 1 34 View
5200120 chr20 28 5 1 34 View
5200121 chr20 28 5 1 34 View
5200122 chr20 28 5 1 34 View
5200254 chr20 110 107 30 247 View
5200776 chr20 28 5 1 34 View
5200778 chr20 28 5 1 34 View
5200780 chr20 28 5 1 34 View
5200781 chr20 28 5 1 34 View
5200782 chr20 28 5 1 34 View
5200784 chr20 28 5 1 34 View
5200785 chr20 28 5 1 34 View
5201711 chr20 26 2 11 39 View
5201712 chr20 4 1 5 View
5201716 chr20 38 38 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of CHMP4B expression and immune infiltrating cell level correlation result in HPV+ samples
CHMP4B expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of CHMP4B expression and immune infiltrating cell level correlation result in HPV+ samples
CHMP4B expression: Low -> High

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of CHMP4B expression and immune infiltrating cell level correlation result in HPV+ samples
CHMP4B expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of CHMP4B expression and immune infiltrating cell level correlation result in HPV+ samples
CHMP4B expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of CHMP4B expression and immune infiltrating cell level correlation result in HPV+ samples
CHMP4B expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of CHMP4B expression and immune infiltrating cell level correlation result in HPV+ samples
CHMP4B expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of CHMP4B expression and immune infiltrating cell level correlation result in HPV+ samples
CHMP4B expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of CHMP4B expression and immune infiltrating cell level correlation result in HPV+ samples
CHMP4B expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of CHMP4B expression and immune infiltrating cell level correlation result in HPV+ samples
CHMP4B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).