HIV Target gene Detail Information

> CHMP2B Gene Search Result

Gene Information

Gene Name	CHMP2B
Gene ID	25978
Gene Full Name	charged multivesicular body protein 2B
Gene Alias	DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5
Transcripts	ENSG00000083937
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9UQN3
HGNC ID	HGNC:24537
VEGA ID	OTTHUMG00000158982
OMIM ID	609512
String ID	9606.ENSP00000263780
PharmGKB ID	PA142672112

Target gene [CHMP2B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009963	chr3	5	4	1	10	View
4013691	chr3	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CHMP2B expression and immune infiltrating cell level correlation result in HIV+ samples
CHMP2B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CHMP2B expression and immune infiltrating cell level correlation result in HIV+ samples
CHMP2B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).