HIV Target gene Detail Information

> CHI3L2 Gene Search Result

Gene Information

Gene Name	CHI3L2
Gene ID	1117
Gene Full Name	chitinase 3 like 2
Gene Alias	CHIL2; YKL39; YKL-39
Transcripts	ENSG00000064886
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q15782
HGNC ID	HGNC:1933
VEGA ID	OTTHUMG00000012174
OMIM ID	601526
String ID	9606.ENSP00000437082
PharmGKB ID	PA26464

Target gene [CHI3L2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001657	chr1	59	36	48	143	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CHI3L2 expression and immune infiltrating cell level correlation result in HIV+ samples
CHI3L2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CHI3L2 expression and immune infiltrating cell level correlation result in HIV+ samples
CHI3L2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).