HIV Target gene Detail Information

> CHD7 Gene Search Result

Gene Information

Gene Name	CHD7
Gene ID	55636
Gene Full Name	chromodomain helicase DNA binding protein 7
Gene Alias	CRG; HH5; IS3; KAL5
Transcripts	ENSG00000171316
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q9P2D1
HGNC ID	HGNC:20626
VEGA ID	OTTHUMG00000165332
OMIM ID	608892
String ID	9606.ENSP00000392028
PharmGKB ID	PA134948695

Target gene [CHD7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006466	chr8	24	1		25	View
4006961	chr8	22			22	View
4016105	chr8				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CHD7 expression and immune infiltrating cell level correlation result in HIV+ samples
CHD7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CHD7 expression and immune infiltrating cell level correlation result in HIV+ samples
CHD7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).