HIV Target gene Detail Information

> CHD6 Gene Search Result

Gene Information

Gene Name	CHD6
Gene ID	84181
Gene Full Name	chromodomain helicase DNA binding protein 6
Gene Alias	CHD5; RIGB; CHD-6
Transcripts	ENSG00000124177
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q8TD26
HGNC ID	HGNC:19057
VEGA ID	OTTHUMG00000032487
OMIM ID	616114
String ID	9606.ENSP00000362330
PharmGKB ID	PA134974700

Target gene [CHD6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000537	chr20	160	92	133	385	View
4011846	chr20	6			6	View
4013807	chr20	2	1		3	View
4015382	chr3		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CHD6 expression and immune infiltrating cell level correlation result in HIV+ samples
CHD6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CHD6 expression and immune infiltrating cell level correlation result in HIV+ samples
CHD6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).