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HIV Target gene Detail Information

> CHD4 Gene Search Result


Gene Information
Gene Name CHD4
Gene ID 1108
Gene Full Name chromodomain helicase DNA binding protein 4
Gene Alias CHD-4; Mi-2b; SIHIWES; Mi2-BETA
Transcripts ENSG00000111642
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q14839
HGNC ID HGNC:1919
VEGA ID OTTHUMG00000169164
OMIM ID 603277
String ID 9606.ENSP00000349508
PharmGKB ID PA26455
Target gene [CHD4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4005541 chr12 23 8 31 View
4009899 chr12 10 10 View
4010392 chr12 6 3 9 View
4100052 chr12 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CHD4 expression and immune infiltrating cell level correlation result in HIV+ samples
CHD4 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CHD4 expression and immune infiltrating cell level correlation result in HIV+ samples
CHD4 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).