HIV Target gene Detail Information

> CEP350 Gene Search Result

Gene Information

Gene Name	CEP350
Gene ID	9857
Gene Full Name	centrosomal protein 350
Gene Alias	GM133; CAP350
Transcripts	ENSG00000135837
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centrosome;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q5VT06
HGNC ID	HGNC:24238
VEGA ID	OTTHUMG00000035269
OMIM ID	617870
String ID	9606.ENSP00000356579
PharmGKB ID	PA143485434

Target gene [CEP350] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000942	chr1	41	140	61	242	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CEP350 expression and immune infiltrating cell level correlation result in HIV+ samples
CEP350 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CEP350 expression and immune infiltrating cell level correlation result in HIV+ samples
CEP350 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).