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HPV Target gene Detail Information

> CEBPB Gene Search Result


Gene Information
Gene Name CEBPB
Gene ID 1051
Gene Full Name CCAAT enhancer binding protein beta
Gene Alias TCF5; IL6DBP; NF-IL6; C/EBP-beta
Transcripts ENSG00000172216
Virus HPV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID P17676
HGNC ID HGNC:1834
VEGA ID OTTHUMG00000032715
OMIM ID 189965
String ID 9606.ENSP00000305422
Drugbank ID BE0005389
PharmGKB ID PA26377
Target gene [CEBPB] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 28767682 C7310T
LCR
G
R
S
C
 View
2 32677948 C7716T
LCR
G
C
 View
3 32677948 C7720A
LCR
G
C
 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of CEBPB expression and immune infiltrating cell level correlation result in HPV+ samples
CEBPB expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of CEBPB expression and immune infiltrating cell level correlation result in HPV+ samples
CEBPB expression: Low -> High

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of CEBPB expression and immune infiltrating cell level correlation result in HPV+ samples
CEBPB expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of CEBPB expression and immune infiltrating cell level correlation result in HPV+ samples
CEBPB expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of CEBPB expression and immune infiltrating cell level correlation result in HPV+ samples
CEBPB expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of CEBPB expression and immune infiltrating cell level correlation result in HPV+ samples
CEBPB expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of CEBPB expression and immune infiltrating cell level correlation result in HPV+ samples
CEBPB expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of CEBPB expression and immune infiltrating cell level correlation result in HPV+ samples
CEBPB expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of CEBPB expression and immune infiltrating cell level correlation result in HPV+ samples
CEBPB expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).