HIV Target gene Detail Information

> CDT1 Gene Search Result

Gene Information

Gene Name	CDT1
Gene ID	81620
Gene Full Name	chromatin licensing and DNA replication factor 1
Gene Alias	DUP; RIS2
Transcripts	ENSG00000167513
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nuclear bodies;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9H211
HGNC ID	HGNC:24576
VEGA ID	OTTHUMG00000173467
OMIM ID	605525
String ID	9606.ENSP00000301019
PharmGKB ID	PA145008572

Target gene [CDT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002801	chr16	79			79	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CDT1 expression and immune infiltrating cell level correlation result in HIV+ samples
CDT1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CDT1 expression and immune infiltrating cell level correlation result in HIV+ samples
CDT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).