HIV Target gene Detail Information

> CDR2 Gene Search Result

Gene Information

Gene Name	CDR2
Gene ID	1039
Gene Full Name	cerebellar degeneration related protein 2
Gene Alias	Yo; CDR62
Transcripts	ENSG00000140743
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q01850
HGNC ID	HGNC:1799
VEGA ID	OTTHUMG00000175463
OMIM ID	117340
String ID	9606.ENSP00000268383
PharmGKB ID	PA26331

Target gene [CDR2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000756	chr16	268	9	13	290	View
4002459	chr16	92		1	93	View
4002849	chr16	77			77	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CDR2 expression and immune infiltrating cell level correlation result in HIV+ samples
CDR2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).