HBV Target gene Detail Information

> CDKN2C Gene Search Result

Gene Information

Gene Name	CDKN2C
Gene ID	1031
Gene Full Name	cyclin dependent kinase inhibitor 2C
Gene Alias	p18; INK4C; p18-INK4C
Transcripts	ENSG00000123080
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	P42773
HGNC ID	HGNC:1789
VEGA ID	OTTHUMG00000008046
OMIM ID	603369
String ID	9606.ENSP00000262662
PharmGKB ID	PA26322

Target gene [CDKN2C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003718	chr1	102	12		114	View
1003965	chr1	90	9		99	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CDKN2C expression and immune infiltrating cell level correlation result in HBV+ samples
CDKN2C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).