HIV Target gene Detail Information

> CDK17 Gene Search Result

Gene Information

Gene Name	CDK17
Gene ID	5128
Gene Full Name	cyclin dependent kinase 17
Gene Alias	PCTK2; PCTAIRE2
Transcripts	ENSG00000059758
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q00537
HGNC ID	HGNC:8750
VEGA ID	OTTHUMG00000170375
OMIM ID	603440
String ID	9606.ENSP00000261211
Drugbank ID	BE0009465
PharmGKB ID	PA33096

Target gene [CDK17] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002754	chr12	60		21	81	View
4004275	chr12	25	5	16	46	View
4004578	chr12	33	9		42	View
4006912	chr12	14	5	3	22	View
4011041	chr12		4	3	7	View
4015251	chr12			1	1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CDK17 expression and immune infiltrating cell level correlation result in HIV+ samples
CDK17 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).