HBV Target gene Detail Information

> CDK13 Gene Search Result


Gene Information
Gene Name CDK13
Gene ID 8621
Gene Full Name cyclin dependent kinase 13
Gene Alias CHED; CDC2L; CDC2L5; hCDK13; CHDFIDD
Transcripts ENSG00000065883
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear speckles;Cytosol;Golgi apparatus;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q14004
HGNC ID HGNC:1733
VEGA ID OTTHUMG00000023726
OMIM ID 603309
String ID 9606.ENSP00000181839
PharmGKB ID PA26264
Target gene [CDK13] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009925 chr7 7 7 14 View
1010995 chr7 2 7 1 10 View
1011221 chr7 2 7 1 10 View
1011352 chr7 2 6 1 9 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CDK13 expression and immune infiltrating cell level correlation result in HBV+ samples
CDK13 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).