HBV Target gene Detail Information

> CDK11B Gene Search Result


Gene Information
Gene Name CDK11B
Gene ID 984
Gene Full Name cyclin dependent kinase 11B
Gene Alias p58; PK58; CDK11; CLK-1; CDC2L1; PITSLREA; p58CLK-1; CDK11-p46; CDK11-p58; p58CDC2L1; CDK11-p110
Transcripts ENSG00000248333
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear speckles;
HPA Protein Class Info Predicted intracellular proteins
HGNC ID HGNC:1729
VEGA ID OTTHUMG00000078638
OMIM ID 176873
String ID 9606.ENSP00000464036
PharmGKB ID PA26262
Target gene [CDK11B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1017013 chr1 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CDK11B expression and immune infiltrating cell level correlation result in HBV+ samples
CDK11B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).