HBV Target gene Detail Information

> CDH6 Gene Search Result


Gene Information
Gene Name CDH6
Gene ID 1004
Gene Full Name cadherin 6
Gene Alias CAD6; KCAD
Transcripts ENSG00000113361
Virus HBV
Gene Type protein coding
HPA Location Info Cell Junctions;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted membrane proteins
Uniport_ID P55285
HGNC ID HGNC:1765
VEGA ID OTTHUMG00000090673
OMIM ID 603007
String ID 9606.ENSP00000265071
PharmGKB ID PA26302
Target gene [CDH6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005761 chr5 20 13 15 48 View
1014506 chr5 3 3 View
1400925 chr5 20 13 15 48 View
1400926 chr5 3 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CDH6 expression and immune infiltrating cell level correlation result in HBV+ samples
CDH6 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).