HBV Target gene Detail Information

> CDH4 Gene Search Result

Gene Information

Gene Name	CDH4
Gene ID	1002
Gene Full Name	cadherin 4
Gene Alias	CAD4; RCAD; R-CAD
Transcripts	ENSG00000280641
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Gene Function	Suppressor gene
Uniport_ID	P55283
HGNC ID	HGNC:1763
VEGA ID	OTTHUMG00000190281
OMIM ID	603006
String ID	9606.ENSP00000484928
PharmGKB ID	PA26300

Target gene [CDH4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002140	chr20	304	11	17	332	View
1010824	chr20	6	3	2	11	View
1011211	chr20	6	4		10	View
1013272	chr20	2	3		5	View
1400345	chr20	9			9	View
1403639	chr20	304	11	17	332	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CDH4 expression and immune infiltrating cell level correlation result in HBV+ samples
CDH4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).