HBV Target gene Detail Information

> CDH12 Gene Search Result


Gene Information
Gene Name CDH12
Gene ID 1010
Gene Full Name cadherin 12
Gene Alias CDHB
Transcripts ENSG00000154162
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted membrane proteins
Uniport_ID P55289
HGNC ID HGNC:1751
VEGA ID OTTHUMG00000090591
OMIM ID 600562
String ID 9606.ENSP00000371689
PharmGKB ID PA26285
Target gene [CDH12] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011567 chr5 1 4 4 9 View
1014952 chr5 2 1 3 View
1017012 chr5 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CDH12 expression and immune infiltrating cell level correlation result in HBV+ samples
CDH12 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).